Endocrine Abstracts

Introduction: Acromegaly is a rare condition characterized by the hypersecretion of growth hormone (GH), resulting in morphological anomalies, metabolic disturbances, including overt diabetes, and endocrine abnormalities.Case Report: We present the case of a 54-year-old patient with a history of cervical lumbar sciatica under treatment. The disease history dates back 3 years with the onset of polyuria-polydipsia syndrome and fatigue. On clinical examinat...

Introduction: Neurofibromatosis type 1(NF1) is an autosomal dominant genodermatosis that affect multiple organs. It represents one of the most frequent genetic diseases. The diagnosis is primarily clinical and is based on the NIH criteria (National Institutes of Health) established in 1988, and revised in 2021. We report a case of male patient with NF1 revealed by a pheochromocytoma.Case Report: A 26-years-old man patient with no previous medical history...

Introduction: Angiosarcomas are aggressive malignant tumors but very rare especially when they are located in the thyroid, characterized histologically by their vascular differentiation and their polymorphic appearance.Observation: We report the case of a 68-years-old female patient, from a mountainous region who has a history of cholecystectomy in 2018, she underwent a total thyroidectomy for a compressive goiter, the postoperative period was marked by ...

Introduction: Primary biliary cholangitis (PBC) is a rare chronic cholestatic liver disease, which is most likely of autoimmune origin. It is often associated with other autoimmune diseases, although it is rarely seen with Basedow.Observation: We report the case of a 38 years old patient, chronic smoker, who presents clinical and biological hyperthyroidism related to Basedow, treated with synthetic antithyroid drugs for years with poor compliance and not...

<table Introduction: Neurofibromatosis type 1 is a multi-organ genetic disease, commonly occurring with variable severity. Pheochromocytoma is a rare manifestation in NF1, affecting 1-15% of NF1 patients according to studies.Case Report: We present 2 cases: - Patient 1: 28 years old, with personal history of café au lait spots, cutaneous and subcutaneous neurofibromas, axillary lentigines. Referred for endocrinology consultation due to an adrenal m...

Introduction: Allgrove syndrome or triple A syndrome is a rare genetic disorder of autosomal recessive inheritance combining in its complete form: esophageal achalasia, alacrymia and adrenal insufficiency.Observation: Patient aged 16, 3rd of 4 siblings from a consanguineous marriage, followed for allograve Sd with megaesophagus operated on in 2016, alacrymia with artificial tears and neurological impairment. As part of the follow-up of his pathology, an ...

Introduction: Micro medullar, thyroid carcinoma is defined as a rare variant of MTC, with a size less than or equal to 1 cm, often incidentall, discovered.Observation: A 67-year-old patient with no medical history presented with two supraclavicular lymph nodes four years ago. A biopsy revealed metastatic tumor proliferation suggestive of a carcinomatous process. Immunohistochemistry confirmed cervical lymph node metastasis of MTC, and further testing sho...

Introduction: Acromegaly is a rare disease defined by the clinical expression of hyperfunction of the somatotropic axis with unchecked secretion of growth hormone. It has many complications, which is why early diagnosis is essential.ObservationWe report the case of a 47-year-old patient, with a history of chronic smoking and renal lithiasis operated on in 2018. His history of illness goes back 3 months to the onset of hypoacusis, which prompted the patient to consult an ENT sp...

Introduction: Galactorrhea is defined as the secretion and flow of milk from the mammary gland in a man or a woman who is not breastfeeding. It is generally due to a pituitary adenoma secreting prolactin. The etiological diagnosis is based on prolactin levels and imaging.Case reportWe report the case of a 42-year-old patient with no notable medical history. His symptoms date back 17 years, marked by the onset of bilateral gynecomastia, spontaneous galactorrhea, and decreased l...

Introduction: A toxic goiter is a goiter that functions autonomously, causing hypersecretion of thyroid hormones, and is almost always benign. We report here the case of a toxic goiter that revealed the presence of papillary thyroid carcinoma.Observation: Patient aged 68, with a history of arterial hypertension, followed for hyperthyroidism on a toxic goitre, with a thyroid scintigraphy showing an enlarged thyroid gland with intense uptake on the right s...